The story of a young boy in the Midwest is told simultaneously with a tale about a young girl in New York from fifty years ago as they both seek the same mysterious connection.

The remake of the 1970 Neil Simon comedy follows the adventures of a couple, Henry and Nancy Clark, vexed by misfortune while in New York City for a job interview.

New York City, in the heart of summer: a heat wave transforms the city into a tropical zone. Ten characters are drawn, one after the other, into a ring of love and desire, each one caught beyond his or her control in a chain reaction of seduction, impulses and self-discovery.

Holly Golightly is a flighty Manhattan party girl, who expects "money for the powder room as well as for cab fare" for her companionship. She has even gotten a lucrative once weekly job to visit notorious convict Sally Tomato in Sing Sing, she needing to report back to Sally's lawyer the weather report that Sally tells her as proof of her visits with him in return for payment. Her aspirations for glamor and wealth are epitomized by the comfort she feels at Tiffany's, the famous high end jewelry...

Ethan (Joseph Gordon-Levitt), Isaac (Seth Rogen) and Chris (Anthony Mackie) have been friends since childhood, and for a decade, their yearly Christmas Eve reunion has been an annual night of debauchery and hilarity. Now that they're entering adulthood, the tradition is coming to an end, and to make it as memorable as possible, they set out to find the Nutcracka Ball - the Holy Grail of Christmas parties.

Tom Popper grew up having very little interaction with his father who was off exploring the world. When he grows up he spends most of time on his work and ignores his children. One day his father sends him an unusual gift: a penguin. Popper can't help but wonder why his father would send him a penguin. He tries to get rid of it, but accidentally orders five more. When his children and ex-wife show up to celebrate his son's birthday, the kids are taken with the penguins. And Popper finally gets...

Nick Lang is a famous Hollywood actor, well known for his action movies. For his next movie, he needs the proper motivation and inspiration for his role. Thus he teams up with the reluctant New York policeman Lt. John Moss. Not only does he have to put up with Nick, who is laborious and out of touch with realities, but he also has to catch a coldblooded murderer.

Gretta (Keira Knightley) and her long-time boyfriend Dave (Adam Levine) are college sweethearts and songwriting partners who decamp for New York when he lands a deal with a major label. But the trappings of his new-found fame soon tempt Dave to stray, and a reeling, lovelorn Gretta is left on her own. Her world takes a turn for the better when Dan (Mark Ruffalo), a disgraced record-label exec, stumbles upon her performing on an East Village stage and is immediately captivated by her raw talent....

When Harry Levine, an aging, unsuccessful Greenwich Village writer is fired from his job as restaurant doorman, he calls on friend and mentor Jake, ostensibly to collect a long-standing debt. Harry solicits his opinion on his latest manuscript, a work of semi-fiction based on their longtime friendship. Although he initially denies having read it, Jake later attacks it on aesthetic grounds, and deep-seated feelings of betrayal and jealousy surface and lead to a traumatic confrontation.